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Decreased Expression of Bmi1 Is Closely Associated with Cellular Senescence in Small Bile Ducts in Primary Biliary Cirrhosis
Cellular senescence of biliary epithelial cells with p16(INK4a) and p21(WAF1/Cip) expression in damaged small bile ducts may be critical for progressive bile duct loss in primary biliary cirrhosis. We investigated the involvement of bmi1, a polycomb group gene repressing p16(INK4a) expression, in th...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698839/ https://ncbi.nlm.nih.gov/pubmed/16936260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051237 |
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