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Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy

Primary biliary cirrhosis (PBC) is characterized by antimitochondrial autoantibodies (AMAs) in patients' sera and histologically by chronic nonsuppurative destructive cholangitis in small bile ducts, eventually followed by extensive bile duct loss and biliary cirrhosis. The autoimmune-mediated...

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Detalhes bibliográficos
Main Authors: Sasaki, Motoko, Nakanuma, Yasuni
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169336/
https://ncbi.nlm.nih.gov/pubmed/21994884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/452143
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