Amyloid-β Peptide Remnants in AN-1792-Immunized Alzheimer’s Disease Patients : A Biochemical Analysis

Experiments with amyloid-β (Aβ)-42-immunized transgenic mouse models of Alzheimer’s disease have revealed amyloid plaque disruption and apparent cognitive function recovery. Neuropathological examination of patients vaccinated against purified Aβ-42 (AN-1792) has demonstrated that senile plaque disr...

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Main Authors: Patton, R. Lyle, Kalback, Walter M., Esh, Chera L., Kokjohn, Tyler A., Van Vickle, Gregory D., Luehrs, Dean C., Kuo, Yu-Min, Lopez, John, Brune, Daniel, Ferrer, Isidro, Masliah, Eliezer, Newel, Amanda J., Beach, Thomas G., Castaño, Eduardo M., Roher, Alex E.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2006
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698828/
https://ncbi.nlm.nih.gov/pubmed/16936277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060269
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