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Chronically Increased Transforming Growth Factor-β1 Strongly Inhibits Hippocampal Neurogenesis in Aged Mice

There is increasing evidence that hippocampal learning correlates strongly with neurogenesis in the adult brain. Increases in neurogenesis after brain injury also correlate with improved outcomes. With aging the capacity to generate new neurons decreases dramatically, both under normal conditions an...

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Autori principali: Buckwalter, Marion S., Yamane, Makiko, Coleman, Bronwen S., Ormerod, Brandi K., Chin, Jocelyn T., Palmer, Theo, Wyss-Coray, Tony
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698757/
https://ncbi.nlm.nih.gov/pubmed/16816369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051272
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