Anomalous Renal Effects of Tin Protoporphyrin in a Murine Model of Sickle Cell Disease

In human and murine models of sickle cell disease (SCD), heme oxygenase-1 (HO-1) is induced in the kidney, an organ commonly involved in SCD. The present study assessed the role of HO-1 by using a competitive inhibitor of HO activity, tin protoporphyrin (SnPP), in protocols affording a composite, cl...

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Autors principals: Juncos, Julio P., Grande, Joseph P., Murali, Narayana, Croatt, Anthony J., Juncos, Luis A., Hebbel, Robert P., Katusic, Zvonimir S., Nath, Karl A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2006
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698751/
https://ncbi.nlm.nih.gov/pubmed/16816358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051195
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