Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin

Secretagogin is a hexa EF-hand protein, which has been identified as a novel potential tumour marker. In the present study, we show that secretagogin binds four Ca(2+) ions (log K(1)=7.1±0.4, log K(2)=4.7±0.6, log K(3)=3.6±0.7 and log K(4)=4.6±0.6 in physiological salt buffers) with a [Ca(2+)](0.5)...

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Hlavní autoři: Rogstam, Annika, Linse, Sara, Lindqvist, Anders, James, Peter, Wagner, Ludwig, Berggård, Tord
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698678/
https://ncbi.nlm.nih.gov/pubmed/16939418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060918
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