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An extended hudrophobic core induces EF-hand swapping
The structure of calbindin D(9k) with two substitutions was determined by X-ray crystallography at 1.8-Å resolution. Unlike wild-type calbindin D(9k), which is a monomeric protein with two EF-hands, the structure of the mutated calbindin D(9k) reveals an intertwined dimer. In the dimer, two EF-hands...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374197/ https://ncbi.nlm.nih.gov/pubmed/11316872 |
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