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Serase-1B, a new splice variant of polyserase-1/TMPRSS9, activates urokinase-type plasminogen activator and the proteolytic activation is negatively regulated by glycosaminoglycans

Polyserase-1 (polyserine protease-1)/TMPRSS9 (transmembrane serine protease 9) is a type II transmembrane serine protease (TTSP) that possesses unique three tandem serine protease domains. However, the physiological function of each protease domain remains poorly understood. We discovered a new spli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Okumura, Yuushi, Hayama, Masaki, Takahashi, Etsuhisa, Fujiuchi, Mieko, Shimabukuro, Aki, Yano, Mihiro, Kido, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698595/
https://ncbi.nlm.nih.gov/pubmed/16872279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060212
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