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Evolutionarily Conserved Role of Nucleostemin: Controlling Proliferation of Stem/Progenitor Cells during Early Vertebrate Development

Nucleostemin (NS) is a putative GTPase expressed preferentially in the nucleoli of neuronal and embryonic stem cells and several cancer cell lines. Transfection and knockdown studies indicated that NS controls the proliferation of these cells by interacting with the p53 tumor suppressor protein and...

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Autores principales: Beekman, Chantal, Nichane, Massimo, De Clercq, Sarah, Maetens, Marion, Floss, Thomas, Wurst, Wolfgang, Bellefroid, Eric, Marine, Jean-Christophe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698517/
https://ncbi.nlm.nih.gov/pubmed/17000755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01183-06
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