Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

It is widely held that cells with metastatic properties such as invasiveness and expression of matrix metalloproteinases arise through the stepwise accumulation of genetic lesions arising from genetic instability and “clonal evolution.” By contrast, we show here that in melanomas invasiveness can be...

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Main Authors: Carreira, Suzanne, Goodall, Jane, Denat, Laurence, Rodriguez, Mercedes, Nuciforo, Paolo, Hoek, Keith S., Testori, Alessandro, Larue, Lionel, Goding, Colin R.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2006
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698449/
https://ncbi.nlm.nih.gov/pubmed/17182868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.406406
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