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Dynamics of the Nucleotide Pocket of Myosin Measured by Spin-Labeled Nucleotides
We have used electron paramagnetic probes attached to the ribose of ATP (SL-ATP) to monitor conformational changes in the nucleotide pocket of myosin. Spectra for analogs bound to myosin in the absence of actin showed a high degree of immobilization, indicating a closed nucleotide pocket. In the Act...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1697850/ https://ncbi.nlm.nih.gov/pubmed/17028139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090035 |
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