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Antigenic Variation of TprK V Regions Abrogates Specific Antibody Binding in Syphilis

The tprK gene in the syphilis spirochete, Treponema pallidum subsp. pallidum, undergoes antigenic variation in seven variable (V) regions. tprK is highly variable within T. pallidum strains, and a method has been developed to derive clones of T. pallidum that express a single, unique tprK sequence....

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Detalhes bibliográficos
Main Authors: LaFond, Rebecca E., Molini, Barbara J., Van Voorhis, Wesley C., Lukehart, Sheila A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1695500/
https://ncbi.nlm.nih.gov/pubmed/16923793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00827-06
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