Protection Elicited by Two Glutamine Auxotrophs of Mycobacterium tuberculosis and In Vivo Growth Phenotypes of the Four Unique Glutamine Synthetase Mutants in a Murine Model

We generated four individual glutamine synthetase (GS) mutants (ΔglnA1, ΔglnA2, ΔglnA3, and ΔglnA4) and one triple mutant (ΔglnA1EA2) of Mycobacterium tuberculosis to investigate the roles of GS enzymes. Subcutaneous immunization with the ΔglnA1EA2 and ΔglnA1 glutamine auxotrophic mutants conferred...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lee, Sunhee, Jeon, Bo-Young, Bardarov, Svetoslav, Chen, Mei, Morris, Sheldon L., Jacobs, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1695480/
https://ncbi.nlm.nih.gov/pubmed/17057098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00531-06
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky