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Some G protein heterotrimers physically dissociate in living cells

Heterotrimeric G proteins mediate physiological processes ranging from phototransduction to cell migration. In the accepted model of G protein signaling, Gαβγ heterotrimers physically dissociate after activation, liberating free Gα subunits and Gβγ dimers. This model is supported by evidence obtaine...

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Detalhes bibliográficos
Main Authors: Digby, Gregory J., Lober, Robert M., Sethi, Pooja R., Lambert, Nevin A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693825/
https://ncbi.nlm.nih.gov/pubmed/17095603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607116103
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