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Mechanisms and regulation of the degradation of cyclin B.

The degradation of the cyclin B subunit of protein kinase Cdk1/cyclin B is required for inactivation of the kinase and exit from mitosis. Cyclin B is degraded by the ubiquitin pathway, a system involved in most selective protein degradation in eukaryotic cells. In this pathway, proteins are targeted...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Hershko, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692665/
https://ncbi.nlm.nih.gov/pubmed/10582242
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