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From neuronal inclusions to neurodegeneration: neuropathological investigation of a transgenic mouse model of Huntington's disease

Huntington's disease (HD) is an inherited progressive neurodegenerative disease caused by the expansion of a polyglutamine repeat sequence within a novel protein. Recent work has shown that abnormal intranuclear inclusions of aggregated mutant protein within neurons is a characteristic feature...

Täydet tiedot

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Bibliografiset tiedot
Päätekijä: Davies, S. W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692612/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.1999.0448
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