Metabolic Engineering of Ammonium Assimilation in Xylose-Fermenting Saccharomyces cerevisiae Improves Ethanol Production

Cofactor imbalance impedes xylose assimilation in Saccharomyces cerevisiae that has been metabolically engineered for xylose utilization. To improve cofactor use, we modified ammonia assimilation in recombinant S. cerevisiae by deleting GDH1, which encodes an NADPH-dependent glutamate dehydrogenase,...

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Veröffentlicht in:	Appl Environ Microbiol
Hauptverfasser:	Roca, Christophe, Nielsen, Jens, Olsson, Lisbeth
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Physiology and Biotechnology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169099/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12902265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.8.4732-4736.2003
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