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Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

Ligand-gated ion channels are a target for inhaled anesthetics and alcohols in the central nervous system. The inhibitory strychnine-sensitive glycine and γ-aminobutyric acid type A receptors are positively modulated by anesthetics and alcohols, and site-directed mutagenesis techniques have identifi...

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Библиографические подробности
Главные авторы: Mascia, Maria Paola, Trudell, James R., Harris, R. Adron
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC16863/
https://ncbi.nlm.nih.gov/pubmed/10908659
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