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Specific binding sites for alcohols and anesthetics on ligand-gated ion channels

Ligand-gated ion channels are a target for inhaled anesthetics and alcohols in the central nervous system. The inhibitory strychnine-sensitive glycine and γ-aminobutyric acid type A receptors are positively modulated by anesthetics and alcohols, and site-directed mutagenesis techniques have identifi...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Mascia, Maria Paola, Trudell, James R., Harris, R. Adron
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.160128797
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