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The correction of hunter fibroblasts by exogenous iduronate sulfate sulfatase: Biochemical and ultrastructural studies

The exogenous addition of iduronate sulfate sulfatase to cultured fibroblasts of Hunter patients resulted in a full correction of the metabolic defect as demonstrated by chemical and ultrastructural analyses. As little as 25% of the normal fibroblasts' enzyme levels were sufficient for this cor...

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Detalhes bibliográficos
Main Authors: Eliahu, Rachel, Sekeles, Eliezer, Cohen, Rachel, Bach, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1685092/
https://ncbi.nlm.nih.gov/pubmed/6789675
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