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In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse

We have identified conditions for forming cultured human umbilical vein endothelial cells (HUVEC) into tubes within a three-dimensional gel that on implantation into immunoincompetent mice undergo remodeling into complex microvessels lined by human endothelium. HUVEC suspended in mixed collagen/fibr...

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Bibliographic Details
Main Authors: Schechner, Jeffrey S., Nath, Anjali K., Zheng, Lian, Kluger, Martin S., Hughes, Christopher C. W., Sierra-Honigmann, M. Rocio, Lorber, Marc I., Tellides, George, Kashgarian, Michael, Bothwell, Alfred L. M., Pober, Jordan S.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC16844/
https://ncbi.nlm.nih.gov/pubmed/10890921
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