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The development of fatal myocarditis and polymyositis in mice heterozygous for IFN-γ and lacking the SOCS-1 gene

Mice lacking the gene encoding the suppressor of cytokine signaling-1 (SOCS-1 −/−) and heterozygous for the IFN–γ gene (IFN-γ +/−) avoided the IFN-γ-dependent preweaning death of SOCS-1 −/− IFN-γ +/+ mice but did not exhibit the good health of young adult SOCS-1 −/− IFN-γ −/− mice. SOCS-1 −/− IFN-γ...

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Bibliografische gegevens
Hoofdauteurs: Metcalf, Donald, Di Rago, Ladina, Mifsud, Sandra, Hartley, Lynne, Alexander, Warren S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16841/
https://ncbi.nlm.nih.gov/pubmed/10908669
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