The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q

We have isolated the human GRAF gene (for GTPase regulator associated with the focal adhesion kinase pp125(FAK)). This gene was fused with MLL in a unique t(5;11)(q31;q23) that occurred in an infant with juvenile myelomonocytic leukemia. GRAF encodes a member of the Rho family of the GTPase-activati...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Borkhardt, Arndt, Bojesen, Stig, Haas, Oskar A., Fuchs, Uta, Bartelheimer, Dominique, Loncarevic, Ivan F., Bohle, Rainer M., Harbott, Jochen, Repp, Reinald, Jaeger, Ulrich, Viehmann, Susanne, Henn, Traudl, Korth, Petra, Scharr, Dirk, Lampert, Fritz
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC16840/
https://ncbi.nlm.nih.gov/pubmed/10908648
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk