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Somatic mosaicism in a patient with bilateral retinoblastoma.

We describe two cell lines with different deletions of the retinoblastoma gene in a patient with bilateral retinoblastoma. This patient has transmitted the mutation less frequent in his lymphocytes to two affected children. We cloned, mapped, and sequenced the junction fragments of the two deletions...

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Bibliografische gegevens
Hoofdauteurs: Greger, V, Passarge, E, Horsthemke, B
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1990
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683849/
https://ncbi.nlm.nih.gov/pubmed/1971154
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