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Frequency of somatic and germ-line mosaicism in retinoblastoma: implications for genetic counseling.

Although mosaicism can have important implications for genetic counseling of families with hereditary disorders, information regarding the incidence of mosaicism is available for only a few genetic diseases. Here we describe an evaluation of 156 families with retinoblastoma; the initial oncogenic mu...

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Detalhes bibliográficos
Main Authors: Sippel, K C, Fraioli, R E, Smith, G D, Schalkoff, M E, Sutherland, J, Gallie, B L, Dryja, T P
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1376960/
https://ncbi.nlm.nih.gov/pubmed/9497263
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