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Huntington disease in Finland: linkage disequilibrium of chromosome 4 RFLP haplotypes and exclusion of a tight linkage between the disease and D4S43 locus.

The question about heterogeneity of Huntington disease (HD) at the DNA level can be approached by analyzing the RFLP haplotypes formed by several RFLP loci of the diseased chromosome in different populations. In genetically isolated populations such as Finland, it is further possible to use this app...

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Detalhes bibliográficos
Main Authors: Ikonen, E, Palo, J, Ott, J, Gusella, J, Somer, H, Karila, L, Palotie, A, Peltonen, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683524/
https://ncbi.nlm.nih.gov/pubmed/1967208
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