Complex patterns of linkage disequilibrium in the Huntington disease region.

The genetic defect causing Huntington disease (HD) has been mapped to 4p16.3 by linkage analysis using DNA markers. Two apparently contradictory classes of recombination events in HD kindreds preclude precise targeting of efforts to clone the disease gene. Here, we report a new recombination event t...

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Autors principals: MacDonald, M E, Lin, C, Srinidhi, L, Bates, G, Altherr, M, Whaley, W L, Lehrach, H, Wasmuth, J, Gusella, J F
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683155/
https://ncbi.nlm.nih.gov/pubmed/1680285
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