Stable expression of pertussis toxin in Bordetella bronchiseptica under the control of a tightly regulated promoter.

Pertussis toxin (PT) is an essential component of accellular vaccines against whooping cough. However, the industrial production of PT from Bordetella pertussis is impaired by slow growth and poor yields. To overcome these problems, we have constructed a minitransposon containing the tox operon unde...

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Bibliographic Details
Main Authors: Suarez, A, Staendner, L H, Rohde, M, Piatti, G, Timmis, K N, Guzmán, C A
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC168309/
https://ncbi.nlm.nih.gov/pubmed/8979346
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