Stable expression of pertussis toxin in Bordetella bronchiseptica under the control of a tightly regulated promoter.

Pertussis toxin (PT) is an essential component of accellular vaccines against whooping cough. However, the industrial production of PT from Bordetella pertussis is impaired by slow growth and poor yields. To overcome these problems, we have constructed a minitransposon containing the tox operon unde...

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Veröffentlicht in:	Appl Environ Microbiol
Hauptverfasser:	Suarez, A, Staendner, L H, Rohde, M, Piatti, G, Timmis, K N, Guzmán, C A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1997
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC168309/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8979346/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.63.1.122-127.1997
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