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Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.

Purine nucleoside phosphorylase (PNP) deficiency is an inherited autosomal recessive disorder resulting in severe combined immunodeficiency. The purpose of this study was to determine the molecular defects responsible for PNP deficiency in one such patient. The patient's PNP cDNA was amplified...

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Detalhes bibliográficos
Main Authors: Aust, M R, Andrews, L G, Barrett, M J, Norby-Slycord, C J, Markert, M L
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682776/
https://ncbi.nlm.nih.gov/pubmed/1384322
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