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Molecular analysis of mutations in a patient with purine nucleoside phosphorylase deficiency.

Purine nucleoside phosphorylase (PNP) deficiency is an inherited autosomal recessive disorder resulting in severe combined immunodeficiency. The purpose of this study was to determine the molecular defects responsible for PNP deficiency in one such patient. The patient's PNP cDNA was amplified...

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Détails bibliographiques
Auteurs principaux: Aust, M R, Andrews, L G, Barrett, M J, Norby-Slycord, C J, Markert, M L
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682776/
https://ncbi.nlm.nih.gov/pubmed/1384322
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