Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent.

Gaussian-process models are developed to detect genetic linkage using complete high-resolution maps of identity by descent between affected relative pairs. Approximations are given for the significance level and power of the likelihood-ratio test of no linkage and for likelihood-ratio confidence reg...

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Bibliographic Details
Main Authors: Feingold, E, Brown, P O, Siegmund, D
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682227/
https://ncbi.nlm.nih.gov/pubmed/8317489
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