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Gaussian models for genetic linkage analysis using complete high-resolution maps of identity by descent.

Gaussian-process models are developed to detect genetic linkage using complete high-resolution maps of identity by descent between affected relative pairs. Approximations are given for the significance level and power of the likelihood-ratio test of no linkage and for likelihood-ratio confidence reg...

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Detalhes bibliográficos
Main Authors: Feingold, E, Brown, P O, Siegmund, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682227/
https://ncbi.nlm.nih.gov/pubmed/8317489
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