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The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HD.

We evaluated the hypothesis that Huntington disease (HD) is influenced by the normal HD allele by comparing transmission patterns of genetically linked markers at the D4S10 locus in the normal parent against age at onset in the affected offspring. Analysis of information from 21 sibships in 14 kindr...

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Detalhes bibliográficos
Main Authors: Farrer, L A, Cupples, L A, Wiater, P, Conneally, P M, Gusella, J F, Myers, R H
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1682222/
https://ncbi.nlm.nih.gov/pubmed/8317477
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