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Residues crucial for maintaining short paths in network communication mediate signaling in proteins
Here, we represent protein structures as residue interacting networks, which are assumed to involve a permanent flow of information between amino acids. By removal of nodes from the protein network, we identify fold centrally conserved residues, which are crucial for sustaining the shortest pathways...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1681495/ https://ncbi.nlm.nih.gov/pubmed/16738564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100063 |
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