Fungal biotransformation of the antihistamine azatadine by Cunninghamella elegans.

The metabolism of the antihistamine azatadine by the zygomycete fungus Cunninghamella elegans ATCC 9245 was investigated. Within 72 h from the addition of the drug to 48-h-old cultures grown in Sabouraud dextrose broth, 95% of azatadine was biotransformed. Two major metabolites, 7-hydroxyazatadine (...

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Detalles Bibliográficos

Publicado en:	Appl Environ Microbiol
Principais autores:	Zhang, D, Hansen, E B, Deck, J, Heinze, T M, Sutherland, J B, Cerniglia, C E
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC168147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8795241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.9.3477-3479.1996
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