Fungal biotransformation of the antihistamine azatadine by Cunninghamella elegans.
The metabolism of the antihistamine azatadine by the zygomycete fungus Cunninghamella elegans ATCC 9245 was investigated. Within 72 h from the addition of the drug to 48-h-old cultures grown in Sabouraud dextrose broth, 95% of azatadine was biotransformed. Two major metabolites, 7-hydroxyazatadine (...
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| Publicado no: | Appl Environ Microbiol |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC168147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8795241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.9.3477-3479.1996 |
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