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The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by motor neuron loss and muscle wasting. In muscles of ALS patients, Nogo-A—a protein known to inhibit axon regeneration—is ectopically expressed at levels that correlate with the severity of the clinical symptoms. We n...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1679784/ https://ncbi.nlm.nih.gov/pubmed/17039253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400826 |
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