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Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers

G-protein-coupled receptors (GPCRs) are important drug targets and are involved in virtually every biological process. However, there are still more than 140 orphan GPCRs, and deciphering their function remains a priority for fundamental and clinical research. Research on orphan GPCRs has concentrat...

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Detalhes bibliográficos
Main Authors: Levoye, Angélique, Dam, Julie, Ayoub, Mohammed A, Guillaume, Jean-Luc, Jockers, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679777/
https://ncbi.nlm.nih.gov/pubmed/17077864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400838
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