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Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B–null mice
Cyclic nucleotide phosphodiesterase 3B (PDE3B) has been suggested to be critical for mediating insulin/IGF-1 inhibition of cAMP signaling in adipocytes, liver, and pancreatic β cells. In Pde3b-KO adipocytes we found decreased adipocyte size, unchanged insulin-stimulated phosphorylation of protein ki...
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Hoofdauteurs: | , , , , , , , , , , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
American Society for Clinical Investigation
2006
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1678809/ https://ncbi.nlm.nih.gov/pubmed/17143332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24867 |
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