Biotransformation of chlorpromazine and methdilazine by Cunninghamella elegans.

When tested as a microbial model for mammalian drug metabolism, the filamentous fungus Cunninghamella elegans metabolized chlorpromazine and methdilazine within 72 h. The metabolites were extracted by chloroform, separated by high-performance liquid chromatography, and characterized by proton nuclea...

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Библиографические подробности

Опубликовано в::	Appl Environ Microbiol
Главные авторы:	Zhang, D, Freeman, J P, Sutherland, J B, Walker, A E, Yang, Y, Cerniglia, C E
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1996
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8975609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.3.798-803.1996
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