Biotransformation of chlorpromazine and methdilazine by Cunninghamella elegans.

When tested as a microbial model for mammalian drug metabolism, the filamentous fungus Cunninghamella elegans metabolized chlorpromazine and methdilazine within 72 h. The metabolites were extracted by chloroform, separated by high-performance liquid chromatography, and characterized by proton nuclea...

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Bibliografski detalji
Glavni autori: Zhang, D, Freeman, J P, Sutherland, J B, Walker, A E, Yang, Y, Cerniglia, C E
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC167846/
https://ncbi.nlm.nih.gov/pubmed/8975609
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