Biotransformation of chlorpromazine and methdilazine by Cunninghamella elegans.
When tested as a microbial model for mammalian drug metabolism, the filamentous fungus Cunninghamella elegans metabolized chlorpromazine and methdilazine within 72 h. The metabolites were extracted by chloroform, separated by high-performance liquid chromatography, and characterized by proton nuclea...
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| Pubblicato in: | Appl Environ Microbiol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC167846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8975609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.62.3.798-803.1996 |
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