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A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development

Nonsense mutations are usually assumed to affect protein function by generating truncated protein products. Nonetheless, it is now clear that these mutations affect not just protein synthesis but also messenger RNA stability. The surveillance mechanism responsible for the detection and degradation o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Alonso, Claudio R., Akam, Michael
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC167643/
https://ncbi.nlm.nih.gov/pubmed/12853602
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