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A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development

Nonsense mutations are usually assumed to affect protein function by generating truncated protein products. Nonetheless, it is now clear that these mutations affect not just protein synthesis but also messenger RNA stability. The surveillance mechanism responsible for the detection and degradation o...

詳細記述

保存先:
書誌詳細
主要な著者: Alonso, Claudio R., Akam, Michael
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC167643/
https://ncbi.nlm.nih.gov/pubmed/12853602
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