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Nonstructural Proteins NS1 and NS2 of Bovine Respiratory Syncytial Virus Block Activation of Interferon Regulatory Factor 3

We have previously shown that the nonstructural (NS) proteins NS1 and NS2 of bovine respiratory syncytial virus (BRSV) mediate resistance to the alpha/beta interferon (IFN)-mediated antiviral response. Here, we show that they, in addition, are able to prevent the induction of beta IFN (IFN-β) after...

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Autors principals: Bossert, Birgit, Marozin, Sabrina, Conzelmann, Karl-Klaus
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC167228/
https://ncbi.nlm.nih.gov/pubmed/12885884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.16.8661-8668.2003
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