A microfluidic-FCS platform for investigation on the dissociation of Sp1-DNA complex by doxorubicin

The transcription factor (TF) Sp1 is a well-known RNA polymerase II transcription activator that binds to GC-rich recognition sites in a number of essential cellular and viral promoters. In addition, direct interference of Sp1 binding to DNA cognate sites using DNA-interacting compounds may provide...

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Bibliografiske detaljer
Main Authors: Yeh, Hsin-Chih, Puleo, Christopher M., Lim, Teck Chuan, Ho, Yi-Ping, Giza, Paul E., Huang, Ru Chih C., Wang, Tza-Huei
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2006
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1669725/
https://ncbi.nlm.nih.gov/pubmed/17108358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl787
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