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A microfluidic-FCS platform for investigation on the dissociation of Sp1-DNA complex by doxorubicin
The transcription factor (TF) Sp1 is a well-known RNA polymerase II transcription activator that binds to GC-rich recognition sites in a number of essential cellular and viral promoters. In addition, direct interference of Sp1 binding to DNA cognate sites using DNA-interacting compounds may provide...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1669725/ https://ncbi.nlm.nih.gov/pubmed/17108358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl787 |
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