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Effects of sulphinpyrazone and aspirin on prostaglandin I2 (prostacyclin) synthesis by endothelial cells.

Synthesis of prostaglandin I2, (PGI2, prostacyclin) by vascular endothelium (assayed by the ability of cultured endothelial cells to inhibit platelet aggregation) was inhibited by aspirin. At 100 mumol/l aspirin completely blocked measurable PGI2 production, but endothelial cells had substantially r...

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Detalles Bibliográficos
Main Authors: Gordon, J L, Pearson, J D
Formato: Artigo
Idioma:Inglês
Publicado: 1978
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1668445/
https://ncbi.nlm.nih.gov/pubmed/365283
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