Thrombogenic Effect of High-Dose Aspirin in Rabbits: RELATIONSHIP TO INHIBITION OF VESSEL WALL SYNTHESIS OF PROSTAGLANDIN I(2)-LIKE ACTIVITY

Aspirin is a promising antithrombogenic agent. It inhibits the generation of thromboxane A(2) by acetylating platelet cyclo-oxygenase. Aspirin also inhibits vessel wall production of PGI(2) which is an inhibitor of platelet aggregation, and therefore is potentially thrombotic. To investigate these t...

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Detalles Bibliográficos
Autores principales: Kelton, J. G., Hirsh, J., Carter, C. J., Buchanan, M. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
Materias:
Rapid Publications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC371843/
https://ncbi.nlm.nih.gov/pubmed/359598
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